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Cold exposure increases circulating irisin. As a result irisin improves insulin sensitivity, which increases bone quality. Also the irisin is involved in the building of lean muscle mass, and helps reduce obesity by converting white fat to brown fat, providing many of the same benefits of exercise. In this way the cold exposure produces a boost on the metabolism, resulting on a leaner body. Is is possible to burn fat fast with out exercising.
BAT Activation
Stands for “Brown adipose tissue activation” which through cold exposure increases adiponectin levels. Just one hour of cold exposure results in a 35% increase in circulating adiponectin in adult men. Centenarians, men and women, have been found to have genetics that boost adiponectin, and they have higher circulating adiponectin, suggesting a link between longevity and adiponectin production. In addition, high concentrations of plasma adiponectin in centenarians was associated with favorable metabolic indicators, and with lower levels of C-reactive protein and E-selectin.
Cold exposure increases SIRT1 phosphorylation activity in both skeletal muscle and BAT, increasing thermogenesis and insulin sensitivity through deacetylation of PGC-1alpha and other protein targets. Elevated SIRT1 levels in people are associated with increased human longevity and in many metabolic effects, but an important one for improving health and longevity is the fact that SIRT1 increases insulin sensitivity and glucose control in skeletal muscles, which triggers the browning of white fat and increases BAT activity.
The Fibroblast Growth Factor 21 Production has been documented as a pathway to longevity. BAT activation through cold exposure up-regulates circulating fibroblast growth factor 21 in humans by 37%. FGF21 improves insulin sensitivity and glucose metabolism which may partially explain its longevity promoting benefits and also impacts the way the body burns the fat.
Cold exposure increases SIRT1 phosphorylation activity in both skeletal muscle and BAT, increasing thermogenesis and insulin sensitivity through deacetylation of PGC-1alpha and other protein targets. Elevated SIRT1 levels in people are associated with increased human longevity and in many metabolic effects, but an important one for improving health and longevity is the fact that SIRT1 increases insulin sensitivity and glucose control in skeletal muscles, which triggers the browning of white fat and increases BAT activity.
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